The simulation hypothesis, like its more esoteric cousin the many-worlds hypothesis are immediately known to be absurd once you are actually in the standpoint that puts the subject prior to the object - so that they form a reduction to absurdity of the opposite stance. The former at least follows almost perfectly from materialism or naturalism as soon as there is an acknowledgment of subjective reality, now become reducible. It is a perfect fit for a certain class of very contemporary metaphysics that is both materialist and accepting of mental reality. You can find out where you are by how peremptorily you reject it, so that it s something like our version of the 'mu' koan. If weakly perfect virtualisation is possible then it is inevitable, and if it is inevitable then the moment you admit your Cartesian subjectivity you are almost surely in a simulation. To which on must only shout 'no!'